9/1/2023 0 Comments Vicorder Manual![]() Risk factors for higher PWV included small for gestational age at birth, secondhand smoking, parental hypertension, and obesity. ![]() ![]() Independent predictors for PWV in a multivariate regression analysis were gender, age, height, weight, mean arterial pressure, and heart rate. Further significant correlations were seen for height, weight, body mass index, blood pressure, pulse pressure, and heart rate. PWV correlated with age (r = 0.57, P < 0.0001) with significant gender-related differences starting at age 9. Gestational and family history was reported. In 589 children carotid distensibility and intima media thickness were measured. Pulse waves were captured in 1,003 healthy children (aged 6-18 years) in 6 centers and gender-specific reference data normalized to age/height were constructed. The Vicorder, an oscillometric device to measure PWV, has been validated in children, but reference values in a large pediatric cohort, association to carotid stiffness and influence of individual and family risk factors have not been determined. Arterial stiffening advances with age and seems accelerated in children with certain disease conditions such as chronic kidney disease or diabetes. Aortic pulse wave velocity (PWV), an indicator of arterial stiffness, independently predicts cardiovascular mortality risk in adults.
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